021-51111890
购物车（）
sales@molnova.cn
A2764 dihydrochloride
CAS No. 861038-72-4
A2764 dihydrochloride ( —— )
产品货号. M21057 CAS No. 861038-72-4
A2764 diHClide 是一种高度选择性的 TRESK 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥300 | 有现货 |
|
| 5MG | ￥478 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
|
| 25MG | ￥1401 | 有现货 |
|
| 50MG | ￥2333 | 有现货 |
|
| 100MG | ￥3629 | 有现货 |
|
| 500MG | ￥7995 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称A2764 dihydrochloride
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A2764 diHClide 是一种高度选择性的 TRESK 抑制剂。
-
产品描述A2764 dihydrochloride is a highly selective inhibitor of TRESK.
-
体外实验A2764 (100 μM) inhibits the background K+ current by 42.8±11.5% when it applies to the oocytes expressing mTRESK.A2764 (100 μM) shows an improvedinhibitory potency for activated channel with an IC50 of activated channel in ionomycin-activated mTRESK current.The subsequent application of A2764 strongly inhibits the current (77.8±3.5%).A2764 (100 μM) inhibits the current of TRESK under resting conditions and in the activated state by 42.8±11.5% and 77.8±3.5%, respectively.
-
体内实验——
-
同义词——
-
通路Cell Cycle/DNA Damage
-
靶点Potassium Channel
-
受体mTRESK channel
-
研究领域——
-
适应症——
化学信息
-
CAS Number861038-72-4
-
分子量351.7
-
分子式C15H21Cl3N2O
-
纯度>98% (HPLC)
-
溶解度DMSO:41.67 mg/mL?(118.48 mM)
-
SMILESCCN(CC)CCOc1ccc(Cl)c2cccnc12.Cl.Cl
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Chemically Modified Derivatives of the Activator Compound Cloxyquin Exert Inhibitory Effect on TRESK (K2P18.1) Background Potassium Channel.[J]. Molecular pharmacology 2019.
产品手册
关联产品
-
Pinacidil monohydrat...
Pinacidil一水合物是一种钾通道激活剂、抗高血压化合物。Pinacidil水合物激活豚鼠膀胱和心脏的ATP调节的钾通道，Ki分别为104和251 nM。
-
Charybdotoxin
Specific inhibitor of the big conductance Ca2+-activated K+ channel.
-
BMS-191095
BMS-191095 是线粒体 ATP 敏感钾 (mitoKATP) 通道激活剂。
